WebDescription: This A1 monoclonal antibody reacts with Ly49A, a 44-kDa member of the Ly49 family of type II transmembrane receptors expressed on natural killer (NK) cells. This … WebIn mice, the activating Ly49H receptor directly interacts with the murine cytomegalovirus (MCMV) m157 gene product on NK cells and confers resistance to MCMV in the C57BL/6 mouse strain which possesses the Ly49h gene ... On the other hand, the 5E6 antibody (to block the inhibitory Ly49I/C signaling) and 1-7F9 antibody ...
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Web10 sept. 2001 · Antibodies. mAbs 3D10 (anti-Ly49H) 28 and 4E4 (anti-Ly49D) 41 were generated and purified by us and either conjugated to fluorescein isothiocyanate (FITC) or biotin (Pierce Chemical, Rockford, IL ... WebInfected C57BL/6 mice treated with anti-Ly49H antibody and mCMV-GFP showed significant progressive hearing loss at 6 weeks after inoculation compared to thresholds 4 weeks after inoculation ( P = 0.001 for DPOAE, P 0.0001 for ABR). The effect of the mCMV-encoded m157 immunoevasin ligand on hearing loss was tested by comparing DPOAE … furniture village corner sofa bed
APC anti-mouse Ly49H Antibody Ly49H, 3D10 - BioLegend
Web10 feb. 2009 · However, these cells respond more robustly upon restimulation with cytokines (IL-12 + IL-15, Fig. 2 C and D) or via engagement of activating NK cell receptors (Ly49H and NK1.1) with plate-bound antibody (Fig. 2 E and F). By comparison, unactivated control-transferred cells had a response similar to endogenous host NK cells. WebWe produced a novel hamster monoclonal antibody (MAb), 14B11, that recognizes the majority of mouse natural-killer (NK) cells. ... In addition, 14B11 was shown to bind the putative activating receptor Ly49H, which required co-transfection of the signaling molecule DAP12 for detectable cell surface expression. Thus, 14B11 is the first reported ... Web11 ian. 2009 · When newborn recipients were treated with an antibody that blocks the Ly49H receptor, protection was abrogated (P = 0.03; Fig. 5f). Thus, like T cells, NK cells have the ability to ‘remember ... giveaway template free download