WebOsteoclasts dissolve bone mineral by massive acid secretion and secrete specialized proteinases that degrade the organic matrix, mainly type I collagen, in this acidic milieu. … WebApr 11, 1997 · An intracellular pathway for proteins liberated from mineralized matrix during resorption was identified in osteoclasts. Analysis by confocal microscopy of sites of active bone resorption showed that released matrix proteins, including degraded type I collagen, were endocytosed along the ruffled border within the resorption compartment and …

5.3 Bone Structure – Introduction to Human Biology

WebA) osteoclasts secrete collagen fibers. B) collagen fibers help organize the deposition of calcium phosphate apatite. C) osteoblasts secrete hydrolytic enzymes creating tunnels … The osteoclasts secrete hydrogen ions, collagenase, cathepsin K and hydrolytic enzymes into this compartment. ... In addition, it permits the vesicular transcytosis of the mineral and degraded collagen from the ruffled border to the free membrane of the cell, and its release into the extracellular compartment. See more An osteoclast (from Ancient Greek ὀστέον (osteon) 'bone', and κλαστός (clastos) 'broken') is a type of bone cell that breaks down bone tissue. This function is critical in the maintenance, repair, and remodeling of See more Since their discovery in 1873 there has been considerable debate about their origin. Three theories were dominant: from 1949 to 1970 the … See more An odontoclast (/odon·to·clast/; o-don´to-klast) is an osteoclast associated with absorption of the roots of deciduous teeth. See more An osteoclast can also be an instrument used to fracture and reset bones (the origin is Greek osteon: bone and klastos: broken). To avoid confusion, the cell was originally termed osotoclast. When the surgical instrument went out of use, the cell became known … See more An osteoclast is a large multinucleated cell and human osteoclasts on bone typically have five nuclei and are 150–200 µm in diameter. When … See more Once activated, osteoclasts move to areas of microfracture in the bone by chemotaxis. Osteoclasts lie in small cavities called Howship's lacunae, formed from the digestion of the underlying bone. The sealing zone is the attachment of the osteoclast's See more Giant osteoclasts can occur in some diseases, including Paget's disease of bone and bisphosphonate toxicity. In cats, abnormal … See more holland 1901

Answered: The primary function of osteoclasts is… bartleby

WebJan 5, 2013 · The osteoblasts move over the matrix of a bone and deposit a protein mixture called osteoid. The osteoid contains a protein called collagen as its major component. … WebAug 25, 2024 · Osteoclasts resorb or break down bone. ... includes molecules such as collagen protein fibers, which give bone its flexibility, and calcium (Ca2 ... No. Osteoblasts secrete a mixture called ... WebJun 8, 2024 · Bone consists of four types of cells: osteoblasts, osteoclasts, osteocytes, and osteoprogenitor (or osteogenic) cells. Each cell type has a unique function and is found in … holland 1902