Robustness in simple biochemical networks

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August undefined, 2024

WebDec 13, 2002 · This single parameter sensitivity is also useful for testing robustness of a biochemical network in the laboratory. ... Barkai N, Leibler S. Robustness in simple biochemical networks. Nature. 1997; 387:913–917. doi: 10.1038/43199. [Google Scholar] Alon U, Surette MG, Barkai N, Leibler S. Robustness in bacterial chemotaxis. ... WebNov 1, 2004 · Key Points. Robustness is a ubiquitous feature of biological systems. It ensures that specific functions of the system are maintained despite external and internal …

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WebMay 1, 2011 · Robustness properties appear across many scales of biological organization, from simple biochemical circuits (robust exact adaptation in bacterial chemotaxis and … WebMay 6, 2011 · The concept of robustness is of significance, in turn, as it is related to many biological phenomena such as canalization, homeostasis, stability, redundancy, and plasticity ( 10 ). Robustness is also relevant for characterizing the dependence between parameter values and system behavior. mandalika circuit fia grade

Robustness of Cellular Functions - ScienceDirect

WebBarkai, N.: Robust in Simple Biochemical Networks. Nature 387, 913–917 (1997) ... A New Measure of the Robustness of Biochemical Networks. Bioinformatics 21, 2698–2705 (2005) CrossRef Google Scholar Download references. Author information. Authors and Affiliations. Intelligent Computing Lab, Hefei Institute of Intelligent Machines, Chinese ... WebApr 10, 2024 · This conclusion remained valid following robustness tests using the spatial econometric model and the method of changing explanatory variables. ... Agricultural machinery is gradually replacing the conventional labor force and using biochemical technology; ... the network of big data promotes the rapid transfer of agricultural surplus … WebApr 13, 2024 · Author summary Steady states often describe the long-term behaviors of biochemical systems, which are typically based on ordinary differential equations. To derive a steady state analytically, significant attention has been given in recent years to network-based approaches. While this approach allows a steady state to be derived as long as a … crispin \u0026 crispinian

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WebMar 1, 2010 · Robustness in simple biochemical networks. Barkai N, Leibler S. Nature, (6636):913-917 1997 MED: 9202424 Robustness in bacterial chemotaxis. Alon U, Surette MG, Barkai N, Leibler S. Nature, (6715):168-171 1999 MED: 9923680 Robust perfect adaptation in bacterial chemotaxis through integral feedback control. ... WebJul 23, 2024 · Intuitively, robustness implies that, even under the effect of external perturbations on the system, no matter how strong or random, said property remains unchanged. In mathematics, properties of... mandaliti e pradoWebNotably, to be effective, an adaptation mechanism must be robust: that is, it must remain functional over a wide range of stimulus levels and be insensitive to variations in the biochemical parameters of the network. A central strategy for realizing robust perfect adaptation is to use integral feedback. crispin torres

"WebJun 1, 1997 · We propose a mechanism for robust adaptation in simple signal transduction networks. We show that this mechanism applies in particular to bacterial chemotaxis. … " - Robustness in simple biochemical networks

Robustness in simple biochemical networks

Stochastic analysis of biochemical reaction networks with …

WebMar 12, 2010 · We thereby describe a large class of robustness-inducing networks that already embraces two quite different biochemical modules for which concentration … WebWe propose a mechanism for robust adaptation in simple signal transduction networks. We show that this mechanism applies in particular to bacterial chemotaxis. This is demonstrated within a quantitative model which explains, in a unified way, many aspects of chemotaxis, including proper responses to chemical gradients.

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WebApr 6, 2014 · 3.1. Stochastic differences in robustness. The network (2.1) demonstrates that biochemical reaction networks satisfying the hypotheses of theorem 3.1, and in which the ACR equilibria are known to be stable, may fail to … WebThe degree of robustness in many biochemical networks can be quantitatively investigated. This can be achieved by characterizing a behavior, a physical or biochemical property …

WebDec 12, 2014 · The robustness of biological systems is epitomized by their ability to function in the presence of a large variability in cellular states (25, 26). Signaling dynamics allow biochemical networks to mitigate variability in the cellular state and thereby maximize the information transmission capacity of signaling networks. WebMar 12, 2010 · We thereby describe a large class of robustness-inducing networks that already embraces two quite different biochemical modules for which concentration …

WebSep 22, 2024 · A large class of robustness-inducing networks that already embraces two quite different biochemical modules for which concentration robustness has been … WebDec 13, 2002 · Robustness of mathematical models of biochemical networks is important for validation purposes and can be used as a means of selecting between different competing models. Tools for quantifying parametric robustness are needed. Two techniques for describing quantitatively the robustness of an oscillatory model were …

WebJun 26, 1997 · Robustness may be a common feature of many key cellular properties and could be crucial for the reliable performance of many biochemical networks. Robust properties of a network will be...

WebSep 18, 2007 · Robustness can be defined as a system's characteristics that maintain one or more of its functions under external and internal perturbations. Under this definition, … crispin st. petersWebSep 21, 2024 · Title: Design Principles Underlying Robust Adaptation of Complex Biochemical Networks Running Head: Design Principles for Robust Network Adaptation Authors: Robyn P. Araujo1,2 and Lance A. Liotta3 1School of Mathematical Sciences, Queensland University of Technology, Brisbane, QLD, 4000, Australia 2Institute of Health … crispin stock priceWebAug 1, 2004 · With respect to robustness, this scenario has advantages over the situation where all the components are soluble. First, bistability is now ensured by the existence of two stable configurations: in one, aggregates are in equilibrium with soluble Cdc2–cyclin B, in the other, aggregates are dissolved. crisp interiorsWebApr 6, 2014 · 3.1. Stochastic differences in robustness. The network (2.1) demonstrates that biochemical reaction networks satisfying the hypotheses of theorem 3.1, and in which the … crispin\u0027s crispian dogWebMay 11, 2012 · To many biologists, robustness is ubiquitous and essential because proteins, cells, biochemical networks, immune systems, organisms, and natural populations exist within changing and sometimes novel conditions under which the maintenance of satisfactory performance will determine persistence or function. crispin tickell funeral crisp investWebJul 9, 2003 · This class is defined for networks with topological parameters γ > 2. These networks can operate with a robust dynamical behavior for which the mean biochemical parameter ρ spans over a large range of values. In particular, networks with a parameter γ > 2.5 would display a robust dynamics for any value of ρ. crispin treviño